Notes on the toxicology of cobalt metal.

Supporting Information 1 Title: Toxicology of Wear Particles of Cobalt-Chromium Alloy Metal-on-Metal Hip Implants Part II: Importance of Physicochemical Properties and Dose in Animal and In Vitro Studies as a Basis for Risk Assessment Authors:

Metal-organic frameworks of cobalt and nickel centers with carboxylate and pyridine functionality linkers: Thermal and physical properties; precursors for metal oxide nanoparticle preparation

This  article  provides  an  overview  on  preparation,  design,  crystal structure  and  properties  of  some  metal-organic  frameworks  of carboxylate coordination polymers mixed with pyridine-functionality linkers  prepared  in  our  laboratory.  The  article  covers  coordination polymers  in  two-  and  three-dimensional  supramolecular architectures. The reported coordination polyme...

Toxicity of cobalt-chromium nanoparticles released from a resurfacing hip implant and cobalt ions on primary human lymphocytes in vitro.

Adverse tissue responses to prostheses wear particles and released ions are important contributors to hip implant failure. In implant-related adverse reactions T-lymphocytes play a prominent role in sustaining the chronic inflammatory response. To further understand the involvement of lymphocytes in metal-on-metal (MoM) implant failure, primary human lymphocytes were isolated and treated with c...

Solubilization of cobalt from tungsten carbide–cobalt powder

Several reviews of the toxicology of cobalt, including toxicokinetic aspects, are available (IARC, 1991; Midtgård & Binderup, 1994; Lauwerys & Lison, 1994; Lison, 1996; Barceloux, 1999). This section will focus on the toxicokinetic data published since the previous IARC evaluation (1991) and potentially relevant for cancer. Particular emphasis will be put on studies that examined the fate of in...

Evaluation of the method for analyzing chromium, cobalt and titanium ion levels in the blood following hip replacement with a metal-on-metal prosthesis.

High-resolution inductively coupled plasma mass spectrometry (HR-ICP-MS) can be used to measure metal ion levels in whole blood, although the accuracy and repeatability of this method is not yet known in the clinical setting. In this study, chromium, cobalt and titanium ion levels were measured in three whole blood samples, each collected at the same moment from 101 patients undergoing total hi...